Fragile X syndrome and fragile X-associated disorders [version 1; referees: 2 approved]
Fragile X syndrome (FXS) is caused by a full mutation on the FMR1 gene and a subsequent lack of FMRP, the protein product of FMR1.FMRP plays a key role cent dyyni in regulating the translation of many proteins involved in maintaining neuronal synaptic connections; its deficiency may result in a range of intellectual disabilities, social deficits, p